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・ Magnesia Litera
・ Magnesia Nova
・ Magnesia on the Maeander
・ Magnesia Prefecture
・ Magnesian Conglomerate
・ Magnesian Escarpment
・ Magnesian Limestone
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・ Magnesium
Magnesium (pharmaceutical preparation)
・ Magnesium acetate
・ Magnesium alloy
・ Magnesium aluminide
・ Magnesium and depression
・ Magnesium aspartate
・ Magnesium benzoate
・ Magnesium bicarbonate
・ Magnesium bromide
・ Magnesium carbonate
・ Magnesium chelatase
・ Magnesium chloride
・ Magnesium chromate
・ Magnesium citrate
・ Magnesium deficiency


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Magnesium (pharmaceutical preparation) : ウィキペディア英語版
Magnesium (pharmaceutical preparation)
Magnesium, as a pharmaceutical preparation, is used to treat conditions including magnesium deficiency and hypomagnesemia, as well as eclampsia. Magnesium is important to health.
Usually in lower dosages, magnesium is commonly included in dietary mineral preparations, including many multivitamin preparations.
==Types of preparations==
In practice, magnesium is given in a salt form together with any of several anionic compounds serving as counter-ions, such as chloride or sulfate ('sulphate' in British English). Nevertheless, magnesium is generally presumed to be the active component. An exception is the administration of magnesium sulfate in barium chloride poisoning,〔(【引用サイトリンク】title=BARIUM CHLORIDE DIHYDRATE 4. First Aid Measures )〕 where sulfate binds to barium to form insoluble barium sulfate.
Magnesium is absorbed orally at about 30% bioavailability from any ''water soluble salt,'' such as magnesium chloride or magnesium citrate. The citrate is the least expensive soluble (high bioavailability) oral magnesium salt available in supplements, with 100 mg and 200 mg magnesium typically contained per capsule or tablet.
Magnesium aspartate, chloride, lactate, citrate and glycinate each have bioavailability 4 times greater than the oxide form and are equivalent to each other per amount of magnesium, though not in price.〔Firoz M, Graber M: "Bioavailability of US commercial magnesium preparations.", Magnesium Research 2001 Dec;14(4):257-62.〕〔Lindberg JS, Zobitz MM, Poindexter JR, Pak CY: "Magnesium bioavailability from magnesium citrate and magnesium oxide.",J Am Coll Nutr. 1990 Feb;9(1):48-55.〕
The ligand of choice for large-scale manufacturers of multivitamins and minerals containing magnesium is the magnesium oxide due to its compactness, high magnesium content by weight, low cost, and ease-of-use in manufacturing. However it is insoluble in water. Insoluble magnesium salts such as magnesium oxide or magnesium hydroxide (milk of magnesia) depend on stomach acid for neutralization before they can be absorbed, and thus are relatively poor oral magnesium sources, on average.
Magnesium sulfate (Epsom salts) is soluble in water. It is commonly used as a laxative, owing to the poor absorption of the sulfate component. In lower doses, they may be used as an oral magnesium source, however.
Intravenous or intramuscular magnesium is generally in the form of magnesium sulfate solution. Intravenous or intramuscular magnesium is completely bioavailable, and effective. It is used in severe hypomagnesemia and eclampsia.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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